Vertebrobasilar Dolichoectasia Presenting Recurrent Episodes of Locked-in syndrome: A Case Report and Literature Review

Ayush Gupta1, Marwa Elnazier2, *, Talita D’Aguiar Rosa2
1 Division of Child Neurology, Department of Neurology, University of Louisville, Kentucky 40202, United States
2 Department of Neurology, University of Louisville, Kentucky 40202, United States

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© 2023 Gupta et al.

open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

* Address correspondence to this author at the Department of Neurology, University of Louisville, Kentucky-40202, 500 South Preston St. HSC-A Bldg. Suite 113 Louisville, KY 40202, United States; Tel: 313-443-5001; E-mail:



Vertebrobasilar Dolichoectasia (VBD) is a rare disorder in which arteries cause dilatation and tortuosity of the blood vessels, which affect posterior circulation.

Case Presentation:

In this case report, we discuss a patient of VBD presenting with transient episodes of quadriparesis, aphasia, and vertigo. She had symptoms specifically when her head was turned towards the right side while waking up. Based on MRI findings and angiography, the patient was diagnosed with VBD.


To conclude, VBD should be considered a differential diagnosis for patients presenting with recurrent transient ischemic attacks, such as locked-in syndrome, without any identifiable cause.

Keywords: Vertebrobasilar dolichoectasia, Transient ischemic attack, Stroke, Neuroimaging, Diagnosis, Patients.