Neuropharmacological Profile of Extracts of Aerial Parts of Convolvulus pluricaulis Choisy in Mice Model



Nasir A Siddiqui 1, Nihal Ahmad 2, Nazia Musthaq 3, Ipshita Chattopadhyaya 3, Rachna Kumria 4, Sumeet Gupta*, 3
1 Department of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh, Kingdom of Saudi Arabia
2 Department of Forensic Medicine and Toxicology, K.M.C.T. Medical College, Manassery, Mukkam, Kerala-673602, India
3 Department of Pharmaceutical Sciences, M.M. College of Pharmacy, M.M. University, Mullana, Ambala, Haryana, India
4 Department of Pharmaceutical Sciences, Swift College of Pharmacy, Rajpura Punjab


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© Siddiqui et al.; Licensee Bentham Open.

open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.

* Address correspondence to this author at the Department of Pharmacology, M. M. College of Pharmacy, M. M. University, Mullana, Ambala, Haryana-133203, India; Tel: 09872620252, 08059930156; Fax: 01731304100; E-mail: sumeetgupta25@gmail.com


Abstract

The plant of Convolvulus pluricaulis Choisy was found to be used by different traditional systems and folklore for the treatment of various disorders. The aim of the present study was to investigate the neuropharmacological activity of various extracts of Convolvulus pluricaulis Choisy in albino mice. The animal behavior was evaluated by locomotor activity, tremors activity, sleep inducing model and anxiolytic activity using standard procedures in experimental animal models. The results revealed that ethanolic and aqueous extract showed promising results in terms of statistical manner when compared with control group. In conclusion, this plant exhibits neuorpharmacological activity in tested animals.

Keywords: Ayurvedic system, mice, neurobehavioral, shankhpushpi..