Spontaneous CSF Collection in the Cervical Spine may Cause Neurological Deficit and Intra-cranial Hypotension

Rasheed Zakaria 1, *, Martin Wilby 1, Nicholas A Fletcher 2
1 Department of Neurosurgery, The Walton Centre NHS Foundation Trust, Liverpool, UK
2 Department of Neurology, The Walton Centre NHS Foundation Trust, Liverpool, UK

Article Metrics

CrossRef Citations:
Total Statistics:

Full-Text HTML Views: 239
Abstract HTML Views: 156
PDF Downloads: 44
Total Views/Downloads: 439
Unique Statistics:

Full-Text HTML Views: 157
Abstract HTML Views: 84
PDF Downloads: 41
Total Views/Downloads: 282

© Zakaria et al.; Licensee Bentham Open.

open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.

* Address correspondence to this author at the Department of Neurosurgery, The Walton Centre NHS Foundation Trust, Lower Lane, Fazakerley, Liver-pool, L9 7LJ; Tel: 0151 525 3611; Fax: 0151 529 5500; E-mail: rzakaria@nhs.net



a case is described of a spontaneously occurring cerebrospinal fluid collection in the ventral cervical spine which caused radiculopathy and spontaneous intracranial hypotension.


a sixty eight year old Caucasian man presented with a 2 year history of proximal upper limb weakness with a his-tory of trivial cervical trauma many years previously.


the patient was investigated with blood tests for causes of peripheral neuropathy, nerve conduction and electro-myography studies, lumbar puncture and MRI of the brain and spine with contrast.


a cerebrospinal fluid collection was identified in the ventral cervical spinal cord causing mass effect associated with cord atrophy and there were signs of spontaneous intracranial hypotension on the MRI brain including subdural cere-brospinal fluid collections, meningeal enhancement and slumped posterior fossa.


this is the first description of a spontaneous spinal fluid collection causing direct compression and cord sig-nal change, manifest as a motor deficit, with intracranial signs of spontaneous hypotension. Spinal imaging is recom-mended in cases of spontaneous intracranial hypotension and cerebrospinal fluid collections in the spine may rarely be a cause of radiculopathy in such cases.

Keywords: Cerebrospinal fluid, radiculopathy, spontaneous intracranial hypotension.