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CASE REPORT

HSV-2 Induced Cerebellitis: A Case Report of HSV-2 Reactivation by SARS-CoV-2 Infection

The Open Neurology Journal 03 Nov 2023 CASE REPORT DOI: 10.2174/011874205X259383231031051625

Abstract

Background:

Herpes simplex virus type 2 rarely causes encephalitis in humans. Some DNA viruses, such as HSV-1 and HSV-2, can be reactivated by COVID-19 infection. SARS-CoV-2 causes a wide spectrum of neurological deficits, such as stroke, delirium, movement disorders, and neuropathy.

Case Presentation:

An unusual manifestation of HSV-2 was diagnosed as cerebellitis in our patient. It was concluded that SARS-CoV-2 can reactivate DNA viruses, such as HSV-2. Here, we reported a 1-year-old female infant with cerebellitis due to herpes simplex virus type 2 infection.

Conclusion:

The patient was treated with intravenous acyclovir and oral prednisolone for three weeks. Finally, during her 9-month neurological follow-up, she was able to walk with minimal ataxia.

Keywords: HSV-2, COVID-19, Cerebellitis, Ataxia, Encephalitis, HSV-1.
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