CASE REPORT
Reworsening of Recurrent Guillain-Barré Syndrome Triggered by COVID-19 Infection
Gian Luca Vita1, Carmen Terranova2, Maria Sframeli1, Antonio Toscano2, Giuseppe Vita1, 2, *
Article Information
Identifiers and Pagination:
Year: 2021Volume: 15
First Page: 48
Last Page: 51
Publisher ID: TONEUJ-15-48
DOI: 10.2174/1874205X02115010048
Article History:
Received Date: 7/4/2021Revision Received Date: 07/7/2021
Acceptance Date: 26/7/2021
Electronic publication date: 10/11/2021
Collection year: 2021
open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Abstract
Introduction:
Guillain-Barré Syndrome (GBS) is an acute, immune-mediated, generalized polyradiculoneuropathy often triggered by a bacterial or viral infection, vaccination, or surgery. During the SARS-CoV-2 pandemic, some patients were reported with GBS associated COVID-19 infection.
Case Presentation:
We report, herein, a patient who had a recurrent GBS after forty years. Intravenous immunoglobulins (IVIg) induced improvement, but her condition worsened suddenly after twenty days, coinciding with a COVID-19 infection. A second IVIg cycle was administered, and she improved again.
Conclusion:
The take-home message is that in the current pandemic, any re-worsening or lack of improvement after appropriate treatment of GBS or possibly other autoimmune neurological diseases must be checked to determine if it is related to COVID-19 infection.