Specific Effects of Anti-Hypertensive Treatment in an Older Patient with Dementia



Jadwiga Attier Zmudka1, *, Jean Marie Sérot1, Salif Dao2, Claire Sorel3, Anne-Sophie Macaret4, Olivier Balédent5
1 Department of Gerontology, General Hospital Saint Quentin, BioFlowImage, University of Picardy Jules Verne, Amiens, France
2 Department of Radiology, General Hospital Saint Quentin, Saint Quentin, France
3 Department of Cardiology, General Hospital Saint Quentin, Saint Quentin, France
4 Department of Neurology, General Hospital Saint Quentin, Saint Quentin, France
5 BioFlowImage Image processing unit, University Hospital & University of Picardy Jules Verne, Amiens, France


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© 2017 Zmudka et al.

open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

* Address correspondence to this author at the Department of gerontology/ BioFlowImage, University of Picardy Jules Verne, Amiens, France; Tel: +336 28 37 48 67; Fax: +333 23 06 74 31; E-mails: j.attier@ch-stquentin.fr, j.a.g.n.a@wp.pl


Abstract

Dementia is one of the most common health problems in the world. Alzheimer’s disease (AD) is the most common form of dementia. The presence of vascular risk factors such as hypertension (HT) may increase the risk of AD [1,2]. The relation between blood pressure (BP) and dementia has been the subject of numerous epidemiological studies, midlife HT is a risk factor for dementia and AD [3-7] but the association between HT and risk of dementia is lower in the older population [8].

A fair modulation of an antihypertensive treatment, based on the cognitive status of the elderly, can avoid multiple complications.

A case of an older for whom cognitive improvement and reduced risk of falls were noticed after mild blood pressure elevation is reported.

Keywords: Hypertension, Dementia, Cerebral blood flow, Stroke, Asprin, MRI.